A unique OPC organic grape seed extract

A unique OPC organic grape seed extract

Activ’Inside recently launches an organic grape seed extract guaranteed with the highest level in OPC,Grape’InsideTM 60P CO, part of the Signature grapeTM range.

 

Activ’Inside has developed a unique organic OPC grape seed extract with the highest amount of Oligomer Proanthocyanidins (OPC) with the most accurate method: >25% by Porter. This extract is a treasure from French grapes and it is also available in 100% organic version. The softest & the most traditional extraction process is used to preserve all the proprieties of the grape. This grape seed extract has powerful multi-tasking benefits like anti-ageing and hypocholesterolemia proprieties and is backed by pending EFSA claims.

“Through our expertise in sourcing, extraction processes, and analysis, we’ve been able to develop such extract and guarantee the highest organic OPC amount on the market”, said Benoit Lemaire, CEO and Business and marketing VP of Activ’Inside.

 

For more on OPC

 

Proanthocyanidins (PACS) are the major phenolic compounds in grape seeds. They generally occur as oligomers and polymers of a basic monomeric unit of flavanols (catechin, epicatechin). Oligomers of proanthocyanidins, known as OPC, are composed by a minimum of 2 monomer units, until a maximum of 10 units.

OPC are potent antioxidants as scientific publications report their capacity to promote secondary antioxidant activity and inhibit oxidative processes. This is why the organic grape seed extract has a high ORAC value: 7500 μmol Trolox/g.

OPC also provide significant hypocholesterolemia effects and are largely associated with the “French paradox”.

 

For more on Porter

Activ’Inside guarantees the OPC levels of its grape seed extracts by the Porter method. While convenient UV methods and vanillin assay overestimate the OPC amount by interacting with other polyphenols, the Porter method is more precise and allows characterizing “real OPC”. All the OPC Signature grapeTM seedextracts offered by Activ’Inside are guaranteed with the Porter method for optimal anti-aging and cardiovascular benefits.

 

 

More on ACTIV’INSIDE

Activ’Inside, a French company specialized in saffron (Crocus sativus L.) and grapes (Vitis vinifera L.), aims to develop innovative natural products with high added value. “We use science, analysis, claims, intellectual property and marketing to create unique products reflecting customers’ need for a fast and safe access to market” says Benoit LEMAIRE, CEO of ACTIV’INSIDE.

At Activ’Inside, innovation and science are at the core of our activity, as demonstrated by our 3 patented active solutions based on sound scientific knowledge, proprietary published studies and related claims: MemophenolTM, for cognitive health, SkinAxTM, for the skin beauty, Safr’insideTM, for mood / quality of sleep / premenstrual comfort.

Active solutions’s website : http://skinax.comI http://memophenol.comI http://safrinside.com

 

 

 

Memophenol™: clinical study in acute dosage

Memophenol™: clinical study in acute dosage

At Beychac et Caillau, the 30th of August 2019

Beychac & Caillau (France), August 28, 2019 – MemophenolTM, the clinically-proven innovative patented solution to prevent the age-related cognitive decline on seniors, is confirmed to act as a booster of cognitive performance. Its effectiveness in acute dosage has been evaluated on students by Activ’Inside in a new clinical study.

 

 

Nowadays, 20% of students use “smart nootropic drugs” as cognitive boosters to stay competitive and focused. These nootropics, mainly Modafinil or Methylphenidate used in pharmaceutical drugs, have potential long-term side effects [Nature journal, 2008]. To offer quick benefits comparable to those of nootropic drugs without their side effects, Activ’Inside proposes its 100% natural & patented formula Memophenol™ to boost students’ cognitive performance in acute dosage.

 

Activ’Inside conducted a randomized, double-blind placebo-controlled crossover clinical study including 30 French graduated students, from 18 to 25 years old. The crossover approach makes the comparison more powerful as students are their own control.  Each student took both placebo & 600mg of MemophenolTMin acute dosage, 90 minutes before a one-hour intense mental effort. Cognitive performance, including working memory, attention & alertness, was assessed by both objective and self-assessment validated tests in exam conditions.

 

In 90 minutes only, MemophenolTMacute supplementation induces booster effects. Objective results show that Memophenol™ significantly maintains higher cognitive performance by 36% when students were supplemented with Memophenol™ compared to the placebo. This gold-standard clinical study not only proved Memophenol™ effectiveness, it also convinced students by its benefits on cognitive performance: students under Memophenol™ supplementation felt significantly more performant by 39%, according to self-assessment results. These clinical results are subject to a new proprietary patent highlighting Memophenol™ quick effectiveness in acute dosage.

 

 

For more on MemophenolTM: www.memophenol.com

 

 

 

More on ACTIV’INSIDE

Activ’Inside, a French company specialized in saffron (Crocus sativus L.) and grapes (Vitis vinifera L.), aims to develop innovative natural products with high added value. “We use science, analysis, claims, intellectual property and marketing to create unique products reflecting customers’ need for a fast and safe access to market” says Benoit LEMAIRE, CEO of ACTIV’INSIDE.

At Activ’Inside, innovation and science are at the core of our activity, as demonstrated by our 3 patented active solutions based on sound scientific knowledge, proprietary published studies and related claims: MemophenolTM, for cognitive health, SkinAxTM, for the skin beauty, Safr’insideTM, for mood / quality of sleep / premenstrual comfort.

Active solutions’s website : http://skinax.comI http://memophenol.comI http://safrinside.com

 

 

 

Memophenol™ finalist at NutraIngredients Awards Asia 2019

Memophenol™ finalist at NutraIngredients Awards Asia 2019

At Beychac et Caillau, the 24th of July 2019

Activ’Inside announces Memophenol™ selection as ingredient of the year for Healthy aging category at the NutraIngredients Awards Asia 2019.

 

Memophenol™ did it again! Over the past 4 years, this is the 3rdselection at a prestigious award for the Activ’Inside star ingredient. Launched in 2016, Memophenol™ has already been awarded twice in Europe. First named as the laureate for “pharmaceutical product” category at Vitafoods 2016, Geneva, Memophenol™ won its second European award at Vitafoods 2017, Geneva, as the ingredient of the year in “Healthy Aging” category.

The second step was to be recognized around the world in the name of all the scientists involved in this long-lasting international consortium led by Activ’Inside. The company took up this challenge successfully in Asia this year. Selected in the same category “Healthy aging”, Memophenol™ is the fruit of 4 years of research, 7 proprietary publications, 2 clinical studies, and 2 international patents. This 100% natural ingredient is a promising way to improve memory and cognitive performance, on young actives and old people.

Bordering on faultless, Memophenol™ is competing as finalist for the Ingredient of the year – Healthy Aging, to be bestowed in Asia on September, 24th2019. Activ’Inside will be present at Vitafoods Asia in Singapore, 25-26 September on booth E2.

 

Active solutions’s website : http://skinax.comI http://memophenol.comI http://safrinside.com

 

 

 

Safr’Inside™: the only encapsulated saffron extract

Safr’Inside™: the only encapsulated saffron extract

At Beychac et Caillau, the 28th of may 2019

Activ’Inside introduced Safr’insideTM, the first encapsulated saffron extract at Vitafoods Europe 2019 in Geneva. Manufactured in France through patented extractionTM process Tech’care that confers a natural encapsulation of saffron volatile and sensitive metabolites, Safr’InsideTM provides an optimized safranal concentration: up to 10 times more than other saffron extracts. 

 

 

saffron Flower encapsulation

So far, saffron extracts used to nutraceutical applications are not sufficiently characterized, and render only part of the active metabolites originally present in Iranian saffron stigmas. This is mainly due to the applied extraction processes that alter most of saffron active metabolites. Such as safranal and crocin, which are highly volatile and/or thermosensitive compounds. To preserve their richness of the raw material (Iranian saffron stigmas), Activ’Inside has developed and patented a soft-extraction process: Tech’care extraction™. Made in France, this process is based on an innovative extraction/absorption combination: during their extraction, saffron metabolites are preserved from heat and solvent alterations thanks to the addition of a carrier. This unique process provides a natural encapsulation of saffron metabolites.

 

 

 


Saffron particles trapped in the maltodextrin support.                                      Saffron particles and support are separated

Preserves and optimizes safranal concentration                                               No protection of saffron volatile metabolites

 

Compared to a classic atomization process in which saffron particles and support are separated, the Tech’care extractionTM process allows saffron particles to be surrounded by the carrier matrix. Such process protects saffron volatile metabolites, especially safranal, and optimizes its concentration in the final extract. According to U-HPLC analysis, Safr’Inside™ is significantly richer in safranal than other saffron extracts: up to 10 times more than Spanish saffron extract.

 

     More on ACTIV’INSIDE

 

Activ’Inside, a French company specialized in saffron (Crocus sativus L.) and grapes (Vitis vinifera L.), aims to develop innovative natural products with high added value. “We use science, analysis, claims, intellectual property and marketing to create unique products reflecting customers’ need for a fast and safe access to market” says Benoit LEMAIRE, CEO of ACTIV’INSIDE.

 

At Activ’Inside, innovation and science are at the core of our activity, as demonstrated by our 3 patented active solutions based on sound scientific knowledge, proprietary published studies and related claims: MemophenolTM, for cognitive health, SkinAxTM, for the skin beauty, Safr’insideTM, for mood / quality of sleep / premenstrual comfort.

 

Active solutions’s website : http://skinax.comI http://memophenol.comI http://safrinside.com

 

 

 

Activ’inside: 4 New Innovations at VITAFOODS 2019

Activ’inside: 4 New Innovations at VITAFOODS 2019

Activ’inside, a creator of difference for the Nutraceutical market, launch 4 new products and applications at VITAFOODS EUROPE 2019 (Geneva, May 7-9): a new crossover clinical study to enhance cognitive performance on students, an organic grape seed extract with a high OPC content, a tasteless & 100% soluble water grape seed extract, and some trendy fast ready-to-use formula.

 

Significant Results on Students Cognitive performance in only 90 Minutes

 

A new proprietary clinical study is now available on the patented ingredient MemophenolTM. This randomized, double-blind crossover placebo controlled clinical study was conducted on students in one shot dosage. Cognitive performance was tested under exams conditions through validated cognitive tests.

Compared to a placebo,  a one shot Memophenol supplementation 90 minutes before exams is sufficient to  : 

  • Significantly increase attention and working memory during at least one hour 
  • Enhance cognitive performance by 36% 

 

 

Organic OPC from Grape Seed Extract

 

Thanks to a dedicated sourcing, Activ’Inside produces a grape seed extract guaranteed with a high polyphenols & OPC contents (60% Polyphenols and 25% OPC-Porter). Porter is the most accurate method to determinate the OPC content. Made in France,this extract is backed by a pending EFSA claim for its anti-aging benefits. This ingredient is available on private labelling formulations.

 

 

 

 

The Tasteless & 100% Water Soluble Grape Seed Extract

 

This 100% water Soluble & tasteless Grape seed extract provides a high amount of flavanol monomers proven by clinical trial for the best bioavailabilit yand antioxidant benefits. This extracts exclusively obtained from champagne grape varieties. 

 

 

 
Fast & Trendy Ready-to-use Formula

 

Activ’inside will present trendy and functional formulas like gummies to have a sensorial and enjoyable experience, liquid shots to boost the cognitive performance on students, instant drinks to offer great tasting product and attractive applications and functional chocolate swith effect on sleep, mood and memory.

 

 

 

More on ACTIV’INSIDE

Activ’Inside, a French company specialized in saffron (Crocus sativus L.) and grapes (Vitis vinifera L.), aims to develop innovative natural products with high added value. “We use science, analysis, claims, intellectual property and marketing to create unique products reflecting customers’ need for a fast and safe access to market” says Benoit LEMAIRE, CEO of ACTIV’INSIDE.

At Activ’Inside, innovation and science are at the core of our activity, as demonstrated by our 3 patented active solutions based on sound scientific knowledge, proprietary published studies and related claims: MemophenolTM, for cognitive health, SkinAxTM, for the skin beauty, Safr’insideTM, for mood / quality of sleep / premenstrual comfort.

ACTIV’INSIDE, Science Inside, Claims Outside.

For more information: www.memophenol.com | www.skinAx.com | www.safrinside.com