Signature grapeTM

Reveal the hidden benefits

Did you know that grape is backed by 14,000 publications, including 330 clinical studies, showing the polyphenols interest in cognitive health, weight management, sport-energy, cardiovascular health, digestion, vision, skin, circulation, anti-aging and sun care.

Thanks to a full expertise on grape (Vitis Vinifera L.) and its location between Bordeaux and Saint Emilion, Activ’Inside has developed a full range of grape extracts coming from all the different parts of the vine – seed, skin, pomace, shoot, leaf – from red and wine cépages (varieties).

Grape (Vitis Vinifera L.) is one of the most cultivated fruit in the world. Vitis Vinifera L. is native from Southern Europe and Western Asia. Human cultivation and use of grape started 8,000 years ago. Its cultivar is mentioned in the bible, and even Egyptian hieroglyphs (2,400 BC) describe its production.

Grape is recognized for its numerous health benefits, in particular for its antioxidant action. It has traditionally been used notably to treat pain and inflammation, as well as rheumatism, eye and skin conditions for centuries. Numerous epidemiological studies recognized a French specificity: the consumption of wine in a certain quantity reduce the incidence of cardiovascular disorders. It’s called “The French Paradox”.

Reveal the hidden benefits of grape

Activ’Inside reveals the richness of all parts of grape and vine in a full range of premium extracts guaranteed with specific profiles in polyphenols.


– Exclusively used for the Signature grape range of extracts.

– The most widely cultivated grape specie, accounting for almost 90% of the world’s cultivated grapes.

– One of the highest polyphenols content among 17 grape species (published data): higher flavanol monomers and OPCs amount compared to American grapes (V. labrusca).

– Most of the 14,000 studies published on grape were conducted with Vitis vinifera grapes.


– Seeds coming from champagne grape: Chardonnay, Pinot noir, Pinot Meunier.

– Higher levels in monomers and OPCs compared to other grape varieties (Merlot, Sauvignon blanc, etc.).

– Higher antioxidant activity (ORAC* value).

Did you know? Signature grape contains a premium grape seed extract from Champagne with the:

  • Highest content in monomers by U-HPLC (≥30%).
  • Highest ORAC* value (ORAC Multiple Radicals: 96,000).


* Oxygen Radical Absorbance Capacity, measured in µmol TE/g.


– Polyphenols amount guaranteed by both UV and U-HPLC characterization.

– 3 UV methods (DO 280, Folin, Porter) used depending on polyphenols selectivity.

– In-house U-HPLC analysis to characterize small polyphenols (monomers, dimers, etc.).

– Identification and characterization of more than 15 metabolites guaranteed.

– Free of adulteration: 100% grape Vitis vinifera L.


– Monomers: highest bioavailable polyphenols as 45% are absorbed compared to 1% for dimers.

– Bioavailability clinically confirmed (proprietary data).

– EFSA pending claims.

Water solubility on selected references.

– Certified organic, kosher, halal on selected references.

Our differences

Activ’Inside proposes several ready-to-use references and the possibility of tailor-made extracts development according to your specifications.

Clinically proven high bioavailability

The power of monomers

Highest concentrations

Monomers ≥ 30% HPLC; ORACMR 96,000 µmol TE/g

Selected French varieties

Chardonnay, Pinot noir, Pinot meunier, Grenache, Syrah

Highly qualified

All methods perfomed

Water soluble references

expanding the range of applications

Naturally resveratrol & viniferin

Only from grape Vitis Vinifera L.

The best price/ performance ratio

Full range of all grape parts, various concentrations

Free of adulterations

Vitis Vinifera L. purity guaranteed

EFSA pending claims

Anti-aging – Cardiovascular – Vascular – Skin beauty – Weight management

Available with different certifications

Organic, Halal, Kosher and Vegan

Health applications

Signature Grape™ extracts are dedicated to numerous health benefits based on European regulation and/or scientific publications :

EFSA pending claim

EFSA pending claim

EFSA pending claim

EFSA pending claim

EFSA pending claim

EFSA pending claim

* EFSA: European Food Safety Authority

Proprietary innovative active ingredients

Activ’Inside has developed 2 innovative active ingredients based on grape for health applications: MemophenolTM and SkinAx2TM.

Memophenol™ is a patented formula of selected French grape and wild blueberry polyphenols-rich extracts, backed by proprietary published studies.

SkinAx2TM is an anti-aging new generation formula combining for the first time primary and secondary antioxidants. With a synergic association of grape flavanols monomers, bioactive SOD, vitamin C and zinc, this patented natural ingredient is backed by published clinical study.

Les informations contenues dans cette page portent sur des ingrédients qui ne sont pas sont destinés à être fournis en tant que tels au consommateur final. Ces informations sont destinées uniquement aux professionnels de santé et aux opérateurs du secteur du complément alimentaire (fabricant ou donneur d’ordre).


Information contained in this page relate to ingredients that are not intended to be supplied as such to the final consumer. These information are intended only for health professionals and operators of the food supplement sector.


Etes-vous un professionnel de santé ou un acteur du secteur du complément alimentaire ? / Are you a health professional or a food supplement actor?