Long before extraction technologies, clinical trials, or functional beverages, mushrooms were already being used to support health, vitality, and resilience. What has changed is not their relevance, but the lens through which they are understood. Today, ancient practice is being reinterpreted through modern science, and the result is one of the fastest-growing functional ingredient categories worldwide.
China represents one of the rare cases in human history where medicinal knowledge was never fully lost. As early as 3000 BC, mushrooms such as Reishi and Shiitake were valued for their health-promoting properties, particularly in relation to immunity, longevity, and balance. These uses were not anecdotal; they were gradually codified and refined.
By the 1st century BC, the Shen Nong Ben Cao Jing formally listed mushrooms within a structured pharmacopoeia, distinguishing between tonic and therapeutic substances. Over successive dynasties, from Han through Qing, this knowledge was continuously transmitted, expanded, and systematized. Methods of cultivation improved, usage protocols became more precise, and mushrooms were embedded into daily health practices rather than reserved for rare interventions. Importantly, this continuity created cultural trust, something that still shapes consumer behavior in Asia today.
Europe’s relationship with mushrooms followed a very different trajectory. Rather than being integrated into medical systems, fungi were historically associated with danger, and superstition. During the Middle Ages, mushrooms became symbolic of witchcraft and the unknown, reinforcing fear rather than curiosity. As a result, medicinal use remained marginal and poorly documented.
Scientific engagement with fungi did not meaningfully begin until the Renaissance, when classification and taxonomy emerged through figures such as Linnaeus and Fries. Even then, mushrooms were approached as objects of categorization, not health. Europe effectively skipped centuries of applied medicinal use, a gap that would only be bridged much later through pharmaceutical discovery rather than nutrition.
The Western perception of fungi shifted dramatically in the 20th century. The discovery of penicillin in 1928 marked a pivotal moment, proving that fungi could produce compounds with profound medical impact. This breakthrough reframed fungi from dangerous organisms into powerful biological factories.
In the decades that followed, other fungal-derived compounds entered mainstream medicine, including cyclosporine for immune modulation and statins for cardiovascular health. At the same time, research in Asia was validating traditional mushroom use through modern clinical frameworks, particularly around polysaccharides and immune response. This period marked the convergence of two previously separate worlds: empirical tradition and laboratory science.

By the late 20th century, functional mushrooms began to move beyond strictly clinical settings and into broader health applications. Research expanded into immunity-stress response, and metabolic health. Mushrooms were no longer viewed as single-purpose agents, but as multi-functional ingredients capable of supporting multiple physiological systems simultaneously.
This shift coincided with changing consumer attitudes toward health. Preventative nutrition, natural solutions, and holistic well-being gained momentum, creating fertile ground for mushrooms to re-enter western markets.
Today, mushroom extracts sit firmly at the center of the functional ingredient economy. The global market was valued at approximately $31.7 billion in 2023 and is projected to exceed $65 billion by 2030, growing at an annual rate of over 11%. Asia-Pacific continues to dominate, reflecting centuries of cultural familiarity, while the United States has emerged as the fastest-growing market globally.
Food and beverage applications currently represent the largest share of revenue, indicating that consumers increasingly prefer mushrooms in familiar, daily formats. Shiitake remains the largest contributor by volume, while Reishi is expected to show the strongest growth, particularly in immunity and stress-support positioning.
Europe and the United States are driving the category’s next phase of growth. In Europe, demand is accelerating across Germany, the UK, France, and Belgium, supported by clean-label expectations and growing acceptance of traditional ingredients backed by science. In the US, the market is expanding rapidly through innovation, particularly in extracts and formulated products targeting immunity, cognition, stress, and non-stimulant energy.
For brands and formulators, the opportunity has moved beyond awareness: success now depends on standardization, efficacy, and execution.
Recent US consumer data confirms that functional mushrooms are moving from niche to normalized. As of April 2024, 37% of consumers report consuming food and beverage products boosted with mushrooms, while 27% say they use mushroom-based dietary supplements. This shows that everyday formats are now the primary entry point into the category, with supplementation following once familiarity and trust are established.
The generational signal is even stronger. Gen Z consumers over-index by more than 10 percentage points, indicating that fuctional mushrooms are not viewed as experimental, but as a natural part of modern wellness routines. For brands and formulators, this reinforces a clear pathway to growth: accessible food and beverage applications supported by transparent sourcing, consistent quality, and credible functional positioning, with strong long-term potential as younger consumers mature into higher-value supplement users.
Functional mushrooms are no longer just ingredients; they are platforms. Their value lies not only in individual bioactive compounds, but in their layered story, thousands of years of use, growing scientific validation, and strong consumer resonance across regions.
Success in for brands and formulators in this category will depend on more than access to raw materials. Standardization, extraction expertise, regulatory clarity, and evidence-led positioning will define the next phase of growth. After millennia of traditional use, functional mushrooms are entering their most commercial era yet.
Sources
–Nutrition Business Journal
–Innova Market Insights
