Crocus sativus L.
  • Active ingredient

Choose an efficient saffron extract that associates proprietary science and premium botanical with neuronutrition & women health claims.
Our patented ingredient, Safr’Inside™, is the only encapsulated saffron extract for the highest concentration of pure safranal (O,2% U-HPLC) acting as a serotonin amplifier.

Mood & Anti-Stress
Digestive Health
Premenstrual Syndrome

What is Safr'Inside™ ?
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    saffron metabolites
    The only encapsulated saffron extract
    Sargol quality (Crocus sativus L.)
    100% Persian saffron
    European sourcing available
    Proprietary U-HPLC method
    More than 25 compounds identified and characterized by our proprietary published U-HPLC method.
    Innovative extraction process
    • Tech'Care™ Extraction
      The only encapsulated saffron extract obtained with a patented soft extraction process allowing to:

      • Preserve the native composition of saffron
      • Retain volatile compounds, such as safranal, usually lost during extraction
      • Protect from alterations

    • Richest extract in safranal

      • Safranal is the most described saffron compound for its action on serotonin amplification.
      • 10 times more safranal in Safr'Inside™ than in non-encapsulated saffron extracts.
      • Analysis by U-HPLC.

      safranal analysis

    Scientifically proven efficiency

    Efficiency confirmed by Science
    • Fluoxetine-like effect
      Saffron efficacy has been also shown to be statistically similar to Fluoxetine and Imipramine, the main pharmaceutical drugs used to treat anxiety & depressive syndromes. These benefits are obtained without any side effect.
      saffron fluoxetine like effect
    • Proprietary clinical study on healthy people
      Randomized double-blind placebo controlled :

      • 56 healthy adults
      • 18-60 years
      • Non-pathological feelings of depression
      • Chronic supplementation (8 weeks): 15 mg twice /day
      • Acute dosage : 30 mg

      Chronic supplementation :

      • Safr’Insidehas a direct action on stress which results in an improvement of the relationships.
      • Safr'Inside™ is bioavailable.
      • There is a correlation between this bioavailability and the improvement of psychological parameters.

      Acute dosage :

      • Efficient within 30 min
      • Safr'Inside™ lowers stress physical impact on heart.

      Proprietary clinical study (Jakson et al, 2020)

      saffron improves mood and social relationships
    Physiological effects of Safrinside™ on stress
    Serotonin booster

    Balance brain neurotransmitters involved in emotional state.

    -50% of serotonin degradation

    safranal serotonine amplification

    Protects neurons against stress induced toxicity

    significant ROS inhibition

    stress saffron
    Activation of the relaxing nervous system

    Maintain homeostasis of the heart frequency during stressful situation.

    within 30 min

    saffron anti stress balance parasympathetic
    Modulation of the gut-brain axis

    Decreases anxiety by restoring a healthy microbiota, notably by boosting Akkermansia

    prebiotic effect

    akkermansia saffron

    Claims Doses & Galenics

    How to use Safr'Inside™ in your food supplement ?
    saffron extract for nutraceutical product
    Anti-Stress & Sleep
    sleep nutraceutical ingredients
    Women Health
    PMS nutraceutical ingredients
    women sexual health nutraceutical ingredients
    Well Being nutrition
    digestive health nutraceutical ingredients

    EFSA pending claims :
    "Contributes to emotional balance."
    "Helps to maintain good comfort before and during menstrual cycle."
    "Helps to find a better sleep."
    "Contributes to relieve menopause symptoms."

    US Structure/Function claims (validated by Venable) :
    "Safr´Inside™ helps with stress management in daily life"
    "Safr’Inside™ supports a normal, healthy attitude during PMS"
    "Helps to promote a feel of calm or serenity"
    Need more claims

    Dose &
    galenic form

    30 mg/day

    Consumer reviews

    Beneficial effects
    confirmed by consumers

    *Consumer test on 50 healthy adults, 30 mg/day during 30 days.

    • After only 15 days
    4/5 results consumer study safrinside
    Consumers are satisfied by the effectiveness* of Safr'Inside™
    • After 30 days
    1/2 results consumer study safrinside
    Consumers felt improvements* in Sleep quality

    Our products
    Our product
    Health benefits
    Premenstrual Syndrome
    Digestive Health
    Mood & Anti-Stress

    Traditional dry extract of saffron. Iranian sargol quality with appellation of origin

    Safr'Inside™ CO
    Premenstrual Syndrome
    Digestive Health
    Mood & Anti-Stress

    European dry extract of saffron with protected appellation of origin

      Contact Us
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