safr'inside logo

Innovative nutraceutical Saffron extract for an anti-stress effect.

Choose an efficient saffron extract that associates proprietary science and premium botanical with neuronutrition & women sexual health claims. Our patented ingredient, Safr’Inside , is the only encapsulated saffron extract for the highest concentration of pure safranal acting as a serotonin amplifier.
finalist nutraingredients awards Asia 2018
finalist nutraingredients awards 2021
What is Safr’Inside™ ?
How to use Safr’Inside™ in your food supplement ?
saffron extract for nutraceutical product
Anti-Stress & Sleep
mood anti stress nutraceutical ingredients
sleep nutraceutical ingredients
Well-being nutrition
PMS nutraceutical ingredients
digestive health nutraceutical ingredients
Healthy aging
women sexual health nutraceutical ingredients

EFSA pending claims :
“Contributes to emotional balance.”
“Helps to maintain good comfort before and during menstrual cycle.”
“Helps to find a better sleep.”
“Contributes to relieve menopause symptoms.”

US Structure/Function claims (validated by Venable) :
“Safr´Inside™ helps with stress management in daily life”
“Helps to promote a feel of calm or serenity”
Need more claims

Dose &
galenic form

30 mg/day

saffron metabolites
saffron international patent pending
The only encapsulated saffron extract
Sargol quality
100% Persian saffron (Crocus sativus L.)
European quality
PDO 100% European origin
Proprietary U-HPLC method
More than 25 compounds identified and characterized by our proprietary published U-HPLC method.
Innovative extraction process
  • Tech'Care™ Extraction
    The only encapsulated saffron thanks to our patented soft extraction process.

    • Protected from alterations
    • Preserves native composition

    richest saffron in safranal crocins
  • Richest extract in safranal

    • Safranal is an active molecule that acts as a serotonin amplifier.
    • 10 times more safranal in Safr’Inside™ than in non-encapsulated saffron extracts.
    • Analysis by U-HPLC.

    richest saffron in safranal
Physiological effects of Safrinside™ on stress
Central action

Balance brain neurotransmitters involved in emotional state.

-50% of serotonin degradation

safranal serotonine amplification
Peripheral action

Control cortisol secretion, the stress hormone.

-44% in cortisol level

safron decrease cortisol level

Fukui et al, 2011

Activation of the relaxing nervous system

Maintain homeostasis of the heart frequency during stressful situation.

within 30 min

saffron parasympathetic tone
Efficiency confirmed by Science
  • Fluoxetine-like effect
    Saffron efficacy has been also shown to be statistically identical to Fluoxetine and Imipramine, the main pharmaceutical drugs used to treat anxiety & depressive syndromes. These benefits are obtained without any side effect.
    saffron fluoxetine like effect
  • Proprietary clinical study on healthy people
    Randomized double-blind placebo controlled :

    • 56 healthy adults
    • 18-60 years
    • Non-pathological feelings of depression
    • Chronic supplementation (8 weeks): 15 mg twice /day
    • Acute dosage : 30 mg


    Chronic supplementation :

    • Safr’Insidehas a direct action on stress which results in an improvement of the relationships.
    • Safr’Inside™ is bioavailable.
    • There is a correlation between this bioavailability and the improvement of psychological parameters.

    Acute dosage :

    • Efficient within 30 min
    • Safr’Inside™ lowers stress physical impact on heart.



    saffron improves mood and social relationships
vegan nutraceutical ingredients
organic nutraceutical ingredients
clean label positioning supplements
halal nutraceutical ingredients
kosher nutraceutical ingredients
made in france nutraceutical ingredients

    Contact Us