Wellbeing nutrition

Premenstrual syndrome

Premenstrual Syndrome (PMS) is a combination of symptoms experienced by women about a week or two before their period. PMS affects more than 90% of women under the form of bloating, headaches, and mood swings. Severe PMS may interfere with daily life including work, school, social activities.


 experienced some form of premenstrual syndrome

of them say they get some sort of PMS symptoms such as bloating, headaches, and moodiness

of women subjected to PMS are concerned by emotional symptoms

Ingredients solutions
Premenstrual syndrome
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Crocus sativus L.

Saffron, Crocus sativus L., has been traditionally used for millennia by Persian medicine to treat pre-menstrual disorders. WHO official monograph recognizes saffron benefits on both emotional and physical symptoms.


Symptoms of PMS have been suggested to be associated with disturbed serotonergic levels. SSRI have been shown to effectively treat physical symptoms and psychosocial functioning, work performance and quality of life for women with PMS. This is why the efficiency of saffron in relieving those symptoms should be attributed to safranal, the saffron metabolite acting on serotonin amplification.

Clinical evidences

In two randomized placebo-controlled clinical studies, saffron confirmed its effectiveness by cutting the severity of PMS by half.


HEALTH CLAIM (pending)

Significantly relieves up to 50% of PMS severity after 2 months of supplementation

organic available
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Premenstrual syndrome
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Achillea millefolium L.
organic only

Traditional medicinal herb used for the symptomatic treatment of spasms associated with menstrual periods. Formulated with Safr’InsideTM for PMS health supplement, the wording “Yarrow contributes to abdominal comfort during the premenstrual period” has been accepted through the notification procedure by the Belgium authorities.

Health claim*   Traditional use   Clinical study

Valeriana officinalis L.
organic available

Valerian have been used since the 11th century for its tranquilizing/sedative properties as well as for PMS. A supplementation of valerian has been clinically shown to be as efficient as mefenamic acid (a drug commonly used for PMS) in pain reduction with a better safety profile.

Traditional use   Clinical study

lemon balm
Lemon Balm
Melissa officinalis L.
organic available

Lemon balm is recommended in traditional medicine to treat menstrual disorders. Recently, a clinical trial has shown that a daily supplementation of lemon balm during 3 menstrual cycles reduces the severity of physical, psychological and social symptoms of PMS.

Traditional use   Clinical study

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